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M94A2340.TXT
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1994-10-25
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Document 2340
DOCN M94A2340
TI Results of three consecutive inquiries for HIV infection sentinel
surveillance among sexually transmitted diseases patients in Porto
Alegre, RS Brazil.
DT 9412
AU Loureiro R; Balsan M; Ramos M; Silveira V; Becker F; Ferreira J
SO Int Conf AIDS. 1994 Aug 7-12;10(1):326 (abstract no. PC0237). Unique
Identifier : AIDSLINE ICA10/94370235
AB OBJECTIVE: Estimate Instantaneous Prevalence of HIV infection over time
in STD patients sentinel population. METHODS: Three inlinked anonymous
cross-sectional tests with a six-month interval between then;
consecutive sampling of the first consultation male patients who seek
care in a free urban STD Clinic; blood collected for VDRL was separeted
and identified only with date and age group (no other identifier to
preserve anonymity). Women were excluded (reduced number of female
patients in the study periods). The sample were achieved in about six
weeks. Screening test: second generation ELISA. Confirmatory test:
Indirect Immunofluorescence. Internal/external quality control was
adopted (State Reference Laboratory). RESULTS: First inquiry
(may-jun,1992): 18 positive in 400 blood samples, prevalence = 4.5%, SD
= 1.04; CI = 2.46-6.54 (95%-alpha = 0.05); 2.80-6.20 (90%-alpha = 0.10).
Second inquiry (nov-dec,1992): 20 in 400 blood samples were positive
with a prevalence of 5.0%; SD = 1.08; CI = 2.88-7.12 (95%-alpha = 0.05);
3.23-6.77 (90%-alpha = 0.10). Third inquiry (may-jun,1993): 22 positive
in 408 blood samples, prevalence: 5.4%; SD = 1.12; CI = 3.21-7.59
(95%-alpha = 0.05); 3.56-7.24 (90%-alpha = 0.10). CONCLUSIONS: The
founds reveals high prevalences among high-risk population, but no
significant difference were observed between the first and the two
subsequent studies. Probabily a six-month interval is very small to
identify prevalence changes in this population. So the decision was to
follow the studies with a twelve-month intervals between eat inquiry. We
demonstrated the feasibility and usefulness of the sentinel surveillance
of HIV infection proposed by GPA/WHO to orient prevention and control
activities. The anonymous inlinked method avoid participation bias.
DE Adult Brazil/EPIDEMIOLOGY Cross-Sectional Studies *Developing
Countries Enzyme-Linked Immunosorbent Assay Human HIV
Infections/*EPIDEMIOLOGY/TRANSMISSION Incidence Male *Population
Surveillance Sexually Transmitted Diseases/*EPIDEMIOLOGY/TRANSMISSION
MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).